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Pharmacokinetics & Biodistribution

SNBL USA offers a comprehensive pharmacokinetics (PK) and biodistribution program to support the development of your compound. From PK/PD screening studies early in the drug development cycle to PK/TK assessment in support of safety pharmacology and toxicology studies, we are positioned to meet your preclinical needs.

PK and biodistribution studies can be performed in a variety of test systems including NHPs, rats, mice and rabbits.

Capacity and Initiation

SNBL USA maintains a PK-dedicated colony of non-naïve NHPs for rapid initiation.

Client-dedicated colonies of NHPs offer:

• Knowledge of your animals’ dosing histories and test article exposures
• Shortened periods of acclimation
• Rapid initiations
• Advanced planning for long term projections of test article needs and program decisions

PK/TK Analyses and Reports

• WinNonLin Professional software program (version 4.0, Pharsight, Inc.)
• Validated, non-compartmental analysis and reporting of PK/TK results
• Comprehensive or summary PK reports available